In a typical nanoconstruct, alendronic acid is conjugated with hydrophilic head moiety of phospholipid that has an ability to self-assemble with hydrophobic polymeric core through its hydrophobic long carbon-chain. Bisphosphonates are a class of osteoporosis drugs such as Boniva (ibandronate), Fosamax (alendronate), Actonel (risedronate) and Reclast (zoledronic acid). It starts after some seemingly minor jaw trauma, but jaw osteonecrosis can quickly decimate a jawbone. Also take two drugs for cholesterol and statins i rattle !! Alendronic acid may put your pregnancy at risk. Its 2.35am here in Kent & I am terrified about what 2moro will bring if I am forced to use AA. so I was looking up side affects of AA which brought me to this site and I dont like what I am reading, so I am going to ring my doctors and have a talk my gut feeling is not to take them. Im 59 and have a very physical job which involves a lot of walking, and I was told by a clinician when I first started treatment that it cant help the spine anyway! It was so frightening my partner called for an ambulance and I was taken to the local hospital, where they hid me in a side room to let me sit and jerk in private. She suggested maybe I stop taking the AS but I already had. Im considering ringing the hospital myself to see if I can have one done. As I was searching through my kitchen drawers, it came to me. Alendronic Acid: View Uses, Side Effects and Medicines | 1mg 6.5 Nature and contents of . Again i had another Dexa scan 2 years ago and it was found i have oesteoporosis in the spine which i feel very worried about it. Looking back over the past four years of this journey, I realised that whenever I took any other tablets my symptoms worsened dramatically. Dosage instructions, including remaining upright for at least 30 minutes and taking with a full glass of water, must be strictly followed. Two hours later, I finally could eat, and drink. So was my face. To my surprise he agreed. But, remember that without medications, you have to supply your body with enough nutrients and exercise to support and strengthen bone growth. Alendronic Acid 70 mg tablets is a tablet containing the active substance alendronic acid (commonly called alendronate) and belongs to a group of non-hormonal medicines called bisphosphonates. Alendronic Acid Has Destroyed My Life (Everything About Alendronic Acid & When To Stop Taking It) by Reana Jean Cuevas You can only stop taking alendronic acid when your doctor says so. No problems with my calcium + vitamin D levels when I started taking medication. I began to take as prescribed and do not have any problems until 6 days after my 4 th dose, I was awakened in the night with uncomfortable, aching wrists. The first indication I had that something was amiss was in September 2009 I took three anti-sickness pills and had some very strange reactions. As far as the AA, its track record shows there have been dental issues in some people. Land degradation also has serious knock-on effects for humans, such as malnutrition, disease, forced migration, cultural damage, and even war. PDF Guidance letter to all dental and medical practitioners regarding Does anyone know if theres a link between the 2 drugs or if theres a suitable alternative? Bisphosponates are prescribed to help your bones stay as strong as possible. Also does anyone know what element of AA gives you the aches and pains so that I know if it will be safer for me to take the Risedronate please? Im now in my 70s and am doing my best to stay out of a wheelchair. Hey Ive been diagnosed with polymialgia rheumatica too i was prescribed predisolone vit d evacol and now AA Im not having any side effects from it yet but reading all of these comments Im worrying about wether I should take the alendronic acid Ive only taken two up to now but have had no problem with it yet It scares you a bit, Hi I have just been precribed alendronic acid I have not taken it yet as I have had a bad cold. I have always looked after my teeth, having paid for a very expensive bridge in 2010 to fill a gap. I was told i had Oesteoporosis of the spine with high risk of a fracture. This is me! Now its probable to be loosing my teeth and I live on social security and am very afraid that my dental health has been irrevocably damaged by this drug. Like a lot of people I was researching AA70 when I came across this group. As I sat up from the bed my head started to pound. reduce the risk of fractures in people with osteoporosis. I decided to stop. I had settled on a very low dose of Seroxat, enough to keep withdrawal at bay but not enough to have a therapeutic effect, because I didnt need one. Stopped now. Worries about alendronic acid | Alendronic Acid | Forums | Patient Did your painn go away after it left your system. Reading these reports,i am now worried.am 63 & After taking AA 70mg per wkfor 2months,& all the awful side effects mentioned here,consultant wants to try zoledronate yearly infusion. Was taken into hospital and because I was taken alendronic they discharged me with 4 Tramadol pain was excruciating..Then I started knocking on doors ring any doctor who would listen no one listen. It got better in the day, but flared up at night for a few nights, then resolved. Where do you live Jane hope you dont mind me asking. I have had several extrane simpthoms after taking alendronic and had to give it up due to a dental treatment. I have taken 2 in total. My advice beware. I too am very healthy woman 67, play golf dance swim walk, so I was upset to be told I had osteoporosis. I Have been taking Alendronic Acid Tablets for 11 months now. He arranged for me to have an MRI and EEG tests, but his opinion was that Seroxat was the likely culprit as he had never seen anything like this before. She had dizzy spells, blackouts, feeling sick etc and doctors said she had Temperol Arteritis. Also, have you researched iodine? I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. All Rights Reserved. Eventually, I Started Pilates and regular walking. I have osteopenia aged 58 and my sister has osteoporosis aged 65, she was prescribed Alendronic Acid with similar side effects. But, theres not enough evidence on this claim. In the meantime her teeth fell outliterally fell outwhat on earth was happening. Am I the only one the suffer from these bad side effects after taking it for the first time. This prompted me to do more research into alendronic acid, but instead of looking up this generic term, I tried the brand name Fosamax. This was long ago and it was a new drug but the GMC told my GP that yes there was a slight risk of an allergic reaction to it. It can support your bones depending on how long you have taken medicine. . I have been on Sertraline 70mg for a few years and as I have asthma my inhaler has been changed to Beclmetasome 100/6. About 3 hours later, I started to feel weird, sort of dizzy. I am worried about it as it seems to be getting worse. Never in my life have I read as many horror stories and am dumbfounded that medication like this is still being prescribed. Fast forward to 2008. I could hardly walk with pain all over my body, felt sick, couldnt eat. Alendronate (Oral Route) Side Effects - Mayo Clinic This way, youll prevent any irritation in your throat or esophagus. My mom who is 76 has taken 7 tablets, she stopped due to pain in her hips legs and groin. I took the tab yesterday &.the strange & heavy uneven rhythm actually woke me up last night. Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions. Following breast cancer they want me to take Aromatase Inhibitor along with a Biphosphonate Clondronate or Zolendronic so my question to everyone out there will these other biphosphonates result in similar pain? 4 days after my 6th dose, I woke up in the night with right hip pain. Cholesterol-lowering medications -- A class of medications known as bile acid sequestrants (including cholestyramine, colestipol, and colesevelam), used to treat high cholesterol, may interfere with normal calcium absorption and increase the loss of calcium in the urine. I was prescribed alendronic acid 1x weekly. This pain was far worse than the pain I experience withOsteoporosis! I thought that my story was a Seroxat story. You can only stop taking alendronic acid when your doctor says so. She had breast cancer over 5 years ago and had a fall recently and broke her wrist. Bizarre feelings in my head, my arms feeling like they didnt belong to me, I felt faint and dizzy, my heart was pounding and had moments when it seemed out of rhythm. Want to take back controle before I find myself surrendering myself to more drugs. Bizarre feelings in my head my heart was pounding and had moments when it seemed out of rhythm. the shaking could be from one of the new meds, but it started slightly in the summer. If you missed a dose, take it the following day and do not double take it to avoid overdosing. I also ate one energice bar. A big thank you to all. If youve taken alendronic acid for 2 years, your bones might still benefit from it for up to 5 years. Next morning extreme pain in my back and kidney area. I wish everybody all the very best and thank you for your feedback. beyond distribution houston tx; bagwell style bowie; alex pietrangelo family; atlas 80v battery run time; Alendronate Uses, Side Effects & Warnings - Drugs.com When I showed this to my GP, he said that is not correct and the book was wrong. The whole remit of Western medicine is to treat symptoms without curing, so that long term profits can be made. The effects of alendronic acid may occur after 1 month of taking it. HELP! I think I will investigate more about Boron like the reviewer above. Like just for a moment I couldnt remember where I kept my masking tape. But its come to my attention that long term , Six hours later, left jaw joint tightness, nerves in teeth/jaw became sensitive (lasted a day), runny stools, dry mouth, calf cramps (at night). My entire body jerked violently as if I was having an epileptic fit, but I was conscious throughout. Your dosing may depend on your age, how severe your bone condition is, other medical conditions you have, and your reaction to the first dose. I wont be taking it as I feel I may be able to find a natural alternative. Newly diagnosed: Hi everyone I'm 57 and have - Bone Health I stopped taking alendronic acid straight away and now wake every morning in the hope that there might be some improvement in my condition. My whole body is sore. The food and drug agency should be aware of this severe health risk and compensation for reconstruction of dental work and monies for pain and suffering should be compensated. I am now using a Naturopathic Bone Protocol supplentation for building bones. Do not take this drug if you have mild to severe kidney problems. It is usually administered as a pill and given to those with conditions that affect the bones like Paget's disease and osteoporosis. pope francis indigenous peoples. Singing, to my deep distress, is now out of the question, along with all the other active things I loved to do. . https://youtu.be/Gb3G2Kv7kU8, Ive just been perscribed alendronic acid 70mg to take one a week..could you tell me if this is seroxat. I have also been taking Adcal tablets for years. It was the most frightening and totally incomprehensible thing to have no control over my limbs at all but as I sit and write this, I realise it has become totally familiar. Anything more and pressure builds in my head, I feel lightheaded, my ears ring and my muscles jerk happily away by themselves. Withdrawal was so extreme that the longest I ever lasted off the drug was seven weeks, the worst of my life. I had a fall/fracture side of leg then DEXA scab and told I had osteoporosis, my reading was -2.6 which I believe is just over normal readings. It can worsen the side effects of alendronic acid in your stomach and prevent the drug from working. She is currently in a lot of pain when she walks. The pain has travelled to her shins since stopping it. In my diary I have written that I felt lightheaded, as if I wasnt getting enough oxygen, and that my arms and head were fizzing. Abstract. I take Alendronic tablets as I had breast cancer and take the tablets for continuing bone health. Alendronate: 7 things you should know - Drugs.com My memory was a little fuzzy. She was put on Alendronic acid as she had a fall broke her wrist and has had breast cancer. Hi You should be able to have a dexa scan every 5 years. It will slow down the breakdown of bones and support the faster growth of new bones in your body. Alendronic acid | C4H13NO7P2 - PubChem Took dose 8 yesterday, and so far so good. Angry moment! Taking alendronic acid can help if you have, or are at risk of developing, osteoporosis. The NHS Dentist has ben very negative and created time consuming visits which are difficult for me to arrange because I have decreasing mobility because of MS. No one my GP or the dentist recommended by my GP have given me no warning about the serious side effects of having dental extractions while taking Aldronic Acid. Drinking alcohol for about two standards per day may increase your risk of bone fractures. 2019 I went to the Dentist with a broken tooth, she told me after an Xray that she could only pull the tooth out as my jaw was crumbling and she could only offer me dentures from now on. Despite the doctor's assurances that it wasn't addictive, I became addicted. Both. Do not just stop taking alendronic acid without your doctors approval. But the following is extract is certainly familiar; l feel I am not listened to andn being my age, Im past bothering about. She is having pain in her legs, hips and groin. I think its great that we can come in here and discuss how we are feeling. Due to cutbacks now prescribed unnamed Alendronic and feel absolutely ghastly. Hello Barbara Like any other drug, alendronic acid comes with mild side effects, which affect 1 in 100 people. So I have decided that it must be the alendronic acid and I have stopped taking them its making my life unbearable. My idea of a short walk had always been an hour and a half in the woods with my dog my favourite footwear was my walking boots. There are 8,218 reported reactions, bear in mind many dont report the side effects to the Yellow Card Scheme. Now on Alendronic 70 weekly. Ive only had one tablet of the Alendronic Acid yesterday, but seem to have quite a few of the side effects so wont have another again, and am miffed to see that people have problems for weeks even after one tablet. I am at the moment still recovering from my fracture as it only been 3wks so if anyone reading this have a build up of pressure on your leg whilst taking these awful tablets seek help before the leg breaks as it will the femur is so so painful take care everyone. There are over 200 million people worldwide who have osteoporosis. I have many what I call, low grade headaches with a distinct feeling of fuzziness, disorientation and have problems concentrating. So, what happens now, does my Osteoporosis get progressively worse over time? Alendronate Side Effects - Drugs.com This is a dangerous drug. I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. I am otherwise healthy and have never taken any meds in my life. After reading the comments I will not be taking it again. Lately, i have been feeling quite unwell, and after having had all sorts of health checks I have now come to the conclusion that my strange symptoms might be due to Alendronic acid. Maybe tomorrow I will get better direction from the physician. I chose the infusions and, after two infusions, the Pagets was seen to be in remission. So whats the point, it sounds like poison. Alendronate works similarly to other bisphosphonate drugs like risedronate, ibandronate, zoledronic acid, pamidronate, and etidronate. My doctor went through the results with me and told me I needed to take alendronic acid. Dentist now tells me my teeth are not strong enough to hold a bridge again. One thing concerns me! It hurts to walk on my feet. Conclusions: Alendronic acid once weekly produced greater BMD increases at both hip and spine sites and greater reductions in bone turnover relative to risedronic acid once weekly. A novel process for the preparation of alendronic acid is disclosed. Applies to alendronate: oral solution, oral tablet, oral tablet effervescent. With the agreement of my GP I have now stopped taking the tablets. It knocked me out so I stopped it. Have been taking alendronic for 14 months now because I had a fall just over 15months ago and broke both knee caps, have been taking them once a week,but I find they make me dizzy so was thinking of stooping them,is this advisable? I thought, as I was 53 and just into the menopause, it would be sensible to have my bones scanned and was shocked to be told I too have osteoporosis in the spine. Hello I am 66 and like many of you am hating taking this drug, I had breast cancer 4 years ago,so am still taking Anastrosil as it was Hormone related,which in turn apparantly helped causing bone density loss, so ws then diagnosed with osteopenia Alendronic Acid 70mg Oral Solution - Summary of Product Characteristics Everything was find. It may put you at risk of jaw bone damage. Is it possible to just stop taking the tablets? Newsletter archive, Data Based Medicine Global Ltd. The wierd thing is that none of my upper teeth seem to have been affected by it. Below are the most common things you can do to care for your bones after you stop taking alendronic acid: You probably want to get rid of taking alendronic acid as soon as possible and do the natural way of treatment to avoid serious side effects in the future. Hi, Ive just discovered this site. Bisphosphonates are often the first treatment you'll be offered if you have weaker bones. I will not be taking another one! Im not going to take another one and just hope these pains gradually wear off. The doctors do say though that we should let them know if we have any. Many thanks, Diagnosed with myasthenia gravis in January and prescribed boat load of tablets. I am taking much more care of myself with exercise an I am totally sugar gluten dairy and alcohol free. That is, when the hospital said I had osteoporosis. how to prove negative lateral flow test. My advice is dont risk your health when the adverse effects are so clearly documented. Due to Covid I only had a telephone consult with an Endocrinologist. Without the support of new bone tissues, your bones become more porous and fragile, making you prone to bone fractures. So, I took it with 12 ounces of water. It belongs to a class of drugs called bisphosphonates. I also found a naturally sourced alternative to the calcium, which is much easier to digest, but its not as strong. but from the start have not felt well, stabbing pains dental probs,aching joints,My dentist referred me to a specialist to have 3 teeth removed,but i lost it in the chair so scared ! Because of how I tend to react and my blood test results, I thought I would research the new meds first and Im now very pleased that I did. I was prescribed alendronic acid as my DEXA scan showed mildish osteoporosis when I started arimidex. I am also diabetic 2 (no drugs diet only) coeliac (wheat and gluten free. I felt pressurised to take it saying that I would suffer as I get older if I didnt take it but I am now wondering if it really does any good. I better print your reviews kind people & put them before my GP & the Liver Consultant who suggested bisphosphonates in the first place!! A blood test followed and the inflammation was evident in the test, but I did not test positive for RA which I was worried about. Alendronic Acid - Take a break! | Birdshot Uveitis Society I thought that I had been duped, once, into taking a drug I probably didnt need for an illness I probably didnt have, a drug that damaged my health. In 2002 I discovered via the internet that I wasn't desperately ill with an anxiety disorder that only Seroxat could fix. Youre description of whip lash injury describes me. Anyhow, if anyone knows what whip lash feels like, this is worse. Im not really happy with the idea of another pill so asked what would happen if I didnt take them and she said I dont know ! What is Alendronic acid 70mg tablets used for? The last two weeks I have felt terribly sick, not eaten much had terrible bloated stomach, one Sunday I felt so ill I had to do a 111 saw a medical person and was given a thorough test being told everthing was ok, I had put it all down to my gallbladder which it wasnt. Fast forward to 2019 stared getting pains from my knees traveled throughout my body into my head thought im going to die. 20 mile house bernadette 0533 929 10 81; best time to visit kodiak island info@reklamcnr.com; grateful dead from the vault box set caner@reklamcnr.com; athens high school basketball roster reklamcnr20@gmail.com After reading about it I returned the box of tabs unused. Alendronic acid (bisphosphonate) is a prescription medication used to help your bones stay as strong as possible. Alendronate is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. She takes Alendronic Acid every week for a year and a half now for her osteoporosis. Its bad enough living with PBC and all that entails for the rest of my life, but to go through what all of you good people have gone through NO WAY DANNO! Same here. Hi. Side effects developed gradually. Stopped AA & CAL3D immediately!! I was told that it was very uncommon what happened to me, and it was my choice to take it again next week or not. If I apply pressure to my temples, my headache lessens. Alendronic acid produces greater effects than risedronic acid - PubMed So I left the surgery with a prescription for alendronic acid and a promise I would have a scan after two years, not the usual three. I left the surgery with a diagnosis of being on the edge of a clinical depression and a prescription for Seroxat. H411 (50%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment . Sight has deteriorated (but attend Moorfields for regular check ups. Hi, my story is very similar but I only found out today that Alendronic Acid has caused my dental problems. I went back to my GP to inform him that I couldnt take them and he readily gave me another prescription for Risedronate 35mg one a week which I am now frightened to take because the possible side effects listed are exactly the same as the AA. Their mode of action is to disrupt normal bone remodeling, which is ultimately detrimental to bone integrity and fracture resistance. However now it is back with a vengeance! Even a couple of paracetamol would make me ill. And of course I was already taking Seroxat, albeit a very small amount. Alendronic acid and teeth extraction : r/askdentists - Reddit Home; About; Program; FAQ; Registration; Sponsorship; Contact; Home; About; Program; FAQ; Registration; Sponsorship . I have taken them for 5+ years and after some research now I discover that the scans can give false readings, i.e.

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